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Benzoyl Peroxide

The most effective over-the-counter acne ingredient, and the one most likely to dry you out and bleach your towels.

INCI: Benzoyl Peroxide · Also known as BPO

What it does

Benzoyl peroxide kills the bacteria involved in inflammatory acne and, unlike antibiotics, resistance does not develop against it. For red, painful spots it outperforms almost everything else available without a prescription.

It is drying, it can be irritating, and it genuinely bleaches fabric — pillowcases, towels and dark shirts. Use white towels and bedding while you are on it, which sounds like a joke and is not.

Higher strength is not better. 2.5% has been shown to work about as well as 10% with far less irritation. Short-contact therapy — applying it as a wash and rinsing after a couple of minutes — is a good compromise for drier skin.

In a routine

Layers well with

  • Ceramides
  • Niacinamide
  • Moisturiser

Do not layer with

  • Retinol
  • Vitamin C

Same routine is fine for some pairs — same step is the problem. Split them morning and evening when in doubt.

Benzoyl Peroxide questions

Can I use benzoyl peroxide with retinol?

Not in the same application — the combination is irritating and can deactivate some retinoids. Alternate nights, or use benzoyl peroxide in the morning and the retinoid in the evening.

Why is 2.5% recommended over 10%?

Because studies show similar effectiveness with substantially less dryness and irritation. The higher strength mostly buys you peeling.

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